Rationale
Clinical and research need for a harmonized TEAS definition.
Study protocol
Protocol and methodological transparency
The study protocol describes the Delphi methodology, expert panel approach, survey rounds, consensus thresholds, data handling, and dissemination plan.
Open Full Protocol on OSFOverview
International Delphi study
The TEAS Consortium protocol sets out the rationale and procedures for developing a consensus operational definition of treatment-emergent affective switch in mood disorders.
The protocol is publicly available through OSF to support transparency, reproducibility, and expert review.
Protocol contents
Panel selection
Criteria and procedure for inviting international experts.
Delphi rounds
Survey structure, rating approach, comments, and item refinement.
Consensus criteria
Predefined thresholds and handling of unresolved items.
Data handling
Confidentiality, aggregate analysis, and reporting principles.
Dissemination
Preparation of a final consensus document and peer-reviewed manuscript.